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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKLN1
All Species:
35.15
Human Site:
Y76
Identified Species:
64.44
UniProt:
Q9UL63
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL63
NP_001138826.1
735
84768
Y76
Q
N
I
T
F
G
K
Y
E
K
T
H
V
C
N
Chimpanzee
Pan troglodytes
XP_001135240
643
74481
D30
F
T
L
K
H
K
I
D
E
Q
M
F
P
C
R
Rhesus Macaque
Macaca mulatta
XP_001098817
735
84767
Y76
Q
N
I
T
F
G
K
Y
E
K
T
H
V
C
N
Dog
Lupus familis
XP_850354
251
28798
Cat
Felis silvestris
Mouse
Mus musculus
O89050
735
84859
Y76
Q
N
I
T
F
G
K
Y
E
K
T
H
V
C
N
Rat
Rattus norvegicus
Q99PV3
735
84815
Y76
Q
N
I
T
F
G
K
Y
E
K
T
H
V
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511026
709
82133
N71
F
G
G
M
N
E
E
N
M
T
E
L
L
S
S
Chicken
Gallus gallus
NP_001025944
733
84525
Y74
Q
S
I
T
F
G
K
Y
E
K
T
H
V
C
N
Frog
Xenopus laevis
NP_001087072
727
84623
Y68
Q
S
I
I
F
G
K
Y
E
K
T
H
V
C
N
Zebra Danio
Brachydanio rerio
NP_997859
729
84358
Y70
L
S
I
T
Y
G
K
Y
E
K
T
H
V
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610801
853
97490
F108
K
K
I
K
F
G
K
F
E
K
S
H
V
C
N
Honey Bee
Apis mellifera
XP_624921
760
87304
Y88
K
T
I
T
F
G
K
Y
E
K
T
H
V
C
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793226
1390
161226
Y80
D
S
I
T
F
G
K
Y
E
K
T
H
V
C
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.3
99.7
33.8
N.A.
99.1
99.3
N.A.
94.1
96.1
89.9
89.1
N.A.
42.3
54
N.A.
32.6
Protein Similarity:
100
87.4
100
34.1
N.A.
99.5
99.8
N.A.
95.7
98.3
95
95.2
N.A.
61.3
70.9
N.A.
41.9
P-Site Identity:
100
13.3
100
0
N.A.
100
100
N.A.
0
93.3
86.6
80
N.A.
66.6
86.6
N.A.
86.6
P-Site Similarity:
100
26.6
100
0
N.A.
100
100
N.A.
20
100
93.3
93.3
N.A.
86.6
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
8
0
85
0
8
0
0
0
0
% E
% Phe:
16
0
0
0
70
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
8
8
0
0
77
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
77
0
0
0
% H
% Ile:
0
0
77
8
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
16
8
0
16
0
8
77
0
0
77
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
31
0
0
8
0
0
8
0
0
0
0
0
0
77
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
47
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
31
0
0
0
0
0
0
0
0
8
0
0
8
8
% S
% Thr:
0
16
0
62
0
0
0
0
0
8
70
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _